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Journal of Nanomaterials - Volume 2014 2014, Article ID 637858, 4 pages -

Research Article

King Abdullah Institute for Nanotechnology, King Saud University, P.O. Box 2454, Riyadh 11451, Saudi Arabia

Department of Physics and Astronomy, King Saud University, Riyadh 11451, Saudi Arabia

Department of Botany and Microbiology, College of Science, King Saud University, Riyadh 11451, Saudi Arabia

Received 16 July 2013; Revised 11 November 2013; Accepted 31 December 2013; Published 9 February 2014

Academic Editor: Do Kim

Copyright © 2014 Maqusood Ahamed et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


We studied the structural and antimicrobial properties of copper oxide nanoparticles CuO NPs synthesized by a very simple precipitation technique. Copper II acetate was used as a precursor and sodium hydroxide as a reducing agent. X-ray diffraction patter XRD pattern showed the crystalline nature of CuO NPs. Field emission scanning electron microscope FESEM and field emission transmission electron microscope FETEM demonstrated the morphology of CuO NPs. The average diameter of CuO NPs calculated by TEM and XRD was around 23 nm. Energy dispersive X-ray spectroscopy EDS spectrum and XRD pattern suggested that prepared CuO NPs were highly pure. CuO NPs showed excellent antimicrobial activity against various bacterial strains Escherichia coli, Pseudomonas aeruginosa, Klebsiella pneumonia, Enterococcus faecalis, Shigella flexneri, Salmonella typhimurium, Proteus vulgaris, and Staphylococcus aureus. Moreover, E. coli and E. faecalis exhibited the highest sensitivity to CuO NPs while K. pneumonia was the least sensitive. Possible mechanisms of antimicrobial activity of CuO NPs should be further investigated.

Autor: Maqusood Ahamed, Hisham A. Alhadlaq, M. A. Majeed Khan, Ponmurugan Karuppiah, and Naif A. Al-Dhabi



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