A Tyrosine-Dependent Riboswitch Controls the Expression of a Tyrosyl-tRNA Synthetase from Acidithiobacillus ferrooxidansReportar como inadecuado




A Tyrosine-Dependent Riboswitch Controls the Expression of a Tyrosyl-tRNA Synthetase from Acidithiobacillus ferrooxidans - Descarga este documento en PDF. Documentación en PDF para descargar gratis. Disponible también para leer online.

Croatica Chemica Acta, Vol.89 No.2 June 2016. -

Expression of aminoacyl-tRNA synthetases is regulated by a variety of mechanisms at the level of transcription or translation. A T-box dependent transcription termination - antitermination riboswitch system that responds to charged - uncharged tRNA regulates expression of aminoacyl tRNA synthetase genes in Gram-positive bacteria. TyrZ, the gene encoding tyrosyl-tRNA synthetase from Acidithiobacillus ferrooxidans, a Gram-negative acidophilic bacterium that participates in bioleaching of minerals, resembles the gene from Bacillus subtilis including the 5-untranslated region encoding the riboswitch. Transcription of A. ferrooxidans tyrZ is induced by the presence of tyrosine by a mechanism involving antitermination of transcription. This mechanism is probably adapted to the low supply of amino acids of acidic environments of autotrophic bioleaching microorganisms.

This work is licensed under a Creative Commons Attribution 4.0 International License.

riboswitch; T-box; TyrRS; acidophilic bacterium; tyrosine



Autor: Paula Bustamante - ; Program of Cellular and Molecular Biology, Institute of Biomedical Sciences, Faculty of Medicine, University

Fuente: http://hrcak.srce.hr/



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