High-Grade Glioma of the Ventrolateral Medulla in an Adult: Case Presentation and Discussion of Surgical ConsiderationsReportar como inadecuado




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Case Reports in Neurological Medicine - Volume 2016 2016, Article ID 6813089, 9 pages -

Case Report

Division of Neurosurgery, University of Missouri School of Medicine, Columbia, MO 65212, USA

University of Missouri School of Medicine, Columbia, MO 65212, USA

Department of Pathology and Anatomical Sciences, University of Missouri School of Medicine, Columbia, MO 65212, USA

Division of Hematology Oncology, University of Missouri School of Medicine, Columbia, MO 65212, USA

Received 27 December 2015; Accepted 3 April 2016

Academic Editor: Mehmet Turgut

Copyright © 2016 Angela Spurgeon et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Background. High-grade gliomas of the brainstem are rare in adults and are particularly rare in the anterolateral medulla. We describe an illustrative case and discuss the diagnostic and treatment issues associated with a tumor in this location, including differential diagnosis, anatomical considerations for options for surgical management, multimodality treatment, and prognosis. Case Description. A 69-year-old woman presented with a 3-week history of progressive right lower extremity weakness. She underwent an open biopsy via a far lateral approach with partial condylectomy, which revealed a glioblastoma. Concurrent temozolomide and radiation were completed; however, she elected to stop her chemotherapy after 5.5 weeks of treatment. She succumbed to her disease 11 months after diagnosis. Conclusions. Biopsy can be performed relatively safely to provide definitive diagnosis to guide treatment, but long-term prognosis is poor.





Autor: Angela Spurgeon, Viet Le, Sanjay Konakondla, Douglas C. Miller, Tamera Hopkins, and N. Scott Litofsky

Fuente: https://www.hindawi.com/



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