A Multiscale Cardiac Model for Fast Personalisation and ExploitationReport as inadecuate

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1 ASCLEPIOS - Analysis and Simulation of Biomedical Images CRISAM - Inria Sophia Antipolis - Méditerranée

Abstract : Computer models of the heart are of increasing interest for clinical applications due to their discriminative and predictive abilities. However a single 3D simulation can be computationally expensive and long, which can make some practical applications such as the personalisation phase, or a sensitivity analysis of mechanical parameters over the simulated behaviour quite slow. In this manuscript we present a multiscale 0D-3D model which allows us to have a reliable and extremely fast approximation of the behaviour of the 3D model under a few simplifying assumptions. We first detail the two different models, then explain the coupling of the two models to get fast 0D approximation of 3D simulations. Finally we demonstrated how the multiscale model can speed-up an efficient optimization algorithm, which enables a fast personalisation of the 3D simulations by leveraging on the advantages of each scale.

Author: Roch Molléro - Xavier Pennec - Hervé Delingette - Nicholas Ayache - Maxime Sermesant -

Source: https://hal.archives-ouvertes.fr/


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