Efficacy of an Extract of Ocimum tenuiflorum OciBest in the Management of General Stress: A Double-Blind, Placebo-Controlled StudyReportar como inadecuado




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Evidence-Based Complementary and Alternative MedicineVolume 2012 2012, Article ID 894509, 7 pages

Research Article

Clinical Pharmacology, OP Chaudhry Hospital and Research Centre, Lucknow 226 015, India

General Medicine and Cardiology, Lucknow 226 001, India

General Medicine, Bhatnagar Nursing Home, Lucknow 226 012, India

Statistics Centre, Institute for Data Computing and Training, Lucknow 226 012, India

Sannidhi, Gurgaon, India

Research and Development Centre, Natural Remedies, Karnataka, Bangalore 560 100, India

Received 20 April 2011; Accepted 12 July 2011

Academic Editor: José Luis Ríos

Copyright © 2012 Ram Chandra Saxena et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

A randomized, double-blind, placebo-controlled study was conducted to evaluate the efficacy of OciBest, an extract of Ocimum tenuiflorum Linn. in symptomatic control of general stress. The participants received either placebo or OciBest ; 1200 mg of actives per day for six weeks. The severity of stress-related symptoms was self-evaluated by patients at weeks 0, 2, 4 and 6 of the trial period using a symptom rating scale. After six weeks of intervention, scores of symptoms such as forgetfulness, sexual problems of recent origin, frequent feeling of exhaustion, and frequent sleep problems of recent origin decreased significantly in OciBest group as compared with placebo group. Also, the total symptom scores of OciBest group revealed significant reduction as compared to placebo group. The overall improvement in OciBest group was found to be 1.6 times or 39% more in the control of general stress symptoms with respect to placebo. No adverse events were reported during the study. The findings revealed that OciBest was found to be effective and well tolerated by all the patients over the six weeks of study period.





Autor: Ram Chandra Saxena, Rakesh Singh, Parveen Kumar, Mahendra P. Singh Negi, Vinod S. Saxena, Periasamy Geetharani, Joseph Joshu

Fuente: https://www.hindawi.com/



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