COGNITIVE FUNCTIONS IN FIRST-EPISODE DEPRESSION AND RECURRENT DEPRESSIVE DISORDER - Descarga este documento en PDF. Documentación en PDF para descargar gratis. Disponible también para leer online.

Psychiatria Danubina, Vol.27 No.1 March 2015. -

Background: Cognitive deficits in the course of depressive disorders affect mainly memory, attention and the frontal functions.

They are associated with both an earlier onset of symptoms and prolonged episodes. The main aim of the study was to verify the

hypothesis of differences in the effectiveness of cognitive processes between patients with a first episode of depression ED-I and

recurrent depressive disorders rDD.

Subjects and methods: The study comprised 210 subjects: patients with ED-I n=60 and patients with rDD n=150. The

assessment of cognitive functions was based on performance of the Trail Making Test, the Stroop Test, the Verbal Fluency Test, the

California Verbal Learning Test CVLT and the digit span from WAIS-R.

Results: There were no statistically significant differences between the analysed groups in the severity of depressive symptoms.

The negative impact of depressive symptoms on the effectiveness of cognitive functions was observed. The ED-I group recorded

better results compared to the rDD group in terms of the speed of information processing, visual-spatial and auditory-verbal memory

and executive functions, auditory-verbal immediate and delayed memory, ability to learn and verbal fluency. The same differences

were observed with respect to the patients from the ED-I group and the patients with the second episode of depression ED-II in the

course of rDD.

Conclusions: There are significant differences in cognitive functioning of patients with a depressive episode and recurrent

depressive disorders. These differences are already visible from the second episode of a major depressive disorder. Memory, verbal

fluency and frontal functions are reduced.

depressive disorders - recurrent depression - cognitive functions

Autor: Monika Talarowska - ; Department of Adult Psychiatry, Medical University of Lodz, Lodz, Poland Marlena Zajączkowska - ; Departme



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