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Infectious Diseases in Obstetrics and Gynecology - Volume 4 1996, Issue 6, Pages 338-346

Obstetrical Case Report Department of Obstetrics and Gynecology, University of Tennessee Medical Center, 1924 Alcoa Highway, Box U-28, Knoxville 37920, TN, United Kingdom

Received 9 July 1996; Accepted 14 January 1997

Copyright © 1996 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Background: Pneumonia is the most common complication of varicella-zoster infection in adults andhas potentially devastating effects when complicating pregnancy. Due to the significant morbidityand mortality associated with this complication during pregnancy and the small number of reportedcases in the literature, we present this report to help educate physicians who care for pregnantwomen.

Cases: Seven patients are presented in this report. These patients presented at various stages inpregnancy, from 17 to 31 weeks of gestation. Three of the patients had unremarkable hospitalcourses. Three of the patients had hospital stays over 21 days in duration. One patient died fromcomplications of varicella pneumonia after 31 days of hospitalization. The obstetric outcomes of the7 patients described include 1 non-viable delivery at 20 weeks gestation, 3 term deliveries, 2 pretermdeliveries, and 1 patient who has not yet delivered. All of the patients presented were treated withintravenous acyclovir therapy. Of the patients described, 3 required intubation and ventilatorysupport. Other complications encountered include disseminated intravascular coagulation DIC,adult respiratory distress syndrome ARDS, metabolic encephalopathy, pneumothorax, superimposedbacterial pneumonia, and sepsis.

Conclusion: The course and treatment of varicella pneumonia complicating pregnancy are discussed.Current recommendations regarding the use of varicella-zoster immune globulin VZIGare also reviewed.

Autor: Teresa J. Schutte, Louise C. Rogers, and Pleas R. Copas



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