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1 ATHENA - Computational Imaging of the Central Nervous System CRISAM - Inria Sophia Antipolis - Méditerranée 2 LIAMA - Brain imaging

Abstract : How to estimate the diffusion Probability Density Function PDF from the q-space DWI signals is an open problem in diffusion MRI field. The diffusion PDF and the diffusion attenuation of dMRI signal is related by 3 dimensional Fourier transform. Diffusion Orientation Transform DOT 2 was proposed based on the assumption of the mono-exponential decay. Thanks to this assumption, PDF profile at a given radius R0 could be calculated analytically. However the estimated PDF is a low-pass filtered PDF. And this kind of low-pass filtering comes from the intrinsic modeling error 2, which is not a well defined filtering. Although DOT has been extended to multi-exponential model 2 and can reduce the modeling error dramatically, a nonlinear fitting needs to be performed for every voxel, which will limit its usefulness. Here we propose a model-free, linear, robust, analytical PDF profile reconstruction method which avoids the exponential or multi-exponential assumption.





Autor: Jian Cheng - Aurobrata Ghosh - Tianzi Jiang - Rachid Deriche -

Fuente: https://hal.archives-ouvertes.fr/



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