Adolescent Loneliness and the Interaction between the Serotonin Transporter Gene 5-HTTLPR and Parental Support: A Replication StudyReportar como inadecuado




Adolescent Loneliness and the Interaction between the Serotonin Transporter Gene 5-HTTLPR and Parental Support: A Replication Study - Descarga este documento en PDF. Documentación en PDF para descargar gratis. Disponible también para leer online.

Gene-by-environment interaction GxEs studies have gained popularity over the last decade, but the robustness of such observed interactions has been questioned. The current study contributes to this debate by replicating the only study on the interaction between the serotonin transporter gene 5-HTTLPR and perceived parental support on adolescents’ peer-related loneliness. A total of 1,111 adolescents 51% boys with an average age of 13.70 years SD = 0.93 participated and three annual waves of data were collected. At baseline, adolescent-reported parental support and peer-related loneliness were assessed and genetic information was collected. Assessment of peer-related loneliness was repeated at Waves 2 and 3. Using a cohort-sequential design, a Latent Growth Curve Model was estimated. Overall, a slight increase of loneliness over time was found. However, the development of loneliness over time was found to be different for boys and girls: girls’ levels of loneliness increased over time, whereas boys’ levels of loneliness decreased. Parental support was inversely related to baseline levels of loneliness, but unrelated to change of loneliness over time. We were unable to replicate the main effect of 5-HTTLPR or the 5-HTTLPR x Support interaction effect. In the Discussion, we examine the implications of our non-replication.



Autor: Annette W. M. Spithoven , Patricia Bijttebier, Wim Van Den Noortgate, Hilde Colpin, Karine Verschueren, Karla Van Leeuwen, Stepha

Fuente: http://plos.srce.hr/



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