Comparison of Optic Disc Morphology of Optic Nerve Atrophy between Compressive Optic Neuropathy and Glaucomatous Optic NeuropathyReportar como inadecuado




Comparison of Optic Disc Morphology of Optic Nerve Atrophy between Compressive Optic Neuropathy and Glaucomatous Optic Neuropathy - Descarga este documento en PDF. Documentación en PDF para descargar gratis. Disponible también para leer online.

Objectives

To compare the optic nerve head ONH structure between compressive optic neuropathy CON and glaucomatous optic neuropathy GON, and to determine whether selected ONH quantitative parameters effectively discriminate between GON and CON, especially CON cases presenting with a glaucoma-like disc.

Methods

We prospectively assessed 34 patients with CON, 34 age-matched patients with moderate or severe GON, and 34 age-matched healthy control subjects. The quantitative parameters of ONH structure were compared using the Heidelberg Retina Tomograph 2 HRT2 and Spectralis optical coherence tomography with an enhanced depth imaging method.

Results

The mean and maximum cup depths of CON were significantly smaller than those with GON P<0.001 and P<0.001, respectively. The distance between Bruch-s membrane opening and anterior surface of the lamina cribrosa BMO-anterior LC of CON was also significantly smaller than that of glaucoma but was similar to that of the healthy group P<0.001 and P = 0.47, respectively. Based on Moorfields regression analysis of the glaucoma classification of HRT2, 15 eyes with CON were classified with a glaucoma-like disc. The cup-disc area ratio did not differ between cases of CON with a glaucoma-like disc and cases of GON P = 0.16, but the BMO-anterior LC and mean and maximum cup depths of CON cases with a glaucoma-like disc were smaller than those in GON P = 0.005, P = 0.003, and P = 0.001, respectively.

Conclusions

Measurements of the cup depths and the LC depth had good ability to differentiate between CON with a glaucoma-like disc and glaucoma. There was no laminar remodeling detected by laminar surface position in the patients with CON compared to those with GON.



Autor: Masayuki Hata , Kazuaki Miyamoto, Akio Oishi, Yukiko Makiyama, Norimoto Gotoh, Yugo Kimura, Tadamichi Akagi, Nagahisa Yoshimura

Fuente: http://plos.srce.hr/



DESCARGAR PDF




Documentos relacionados