High-Grade Transformation Dedifferentiation of Acinic Cell Carcinoma of the Parotid Gland: Report of an Unusual VariantReportar como inadecuado




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Case Reports in Otolaryngology - Volume 2017 2017, Article ID 7296467, 4 pages - https:-doi.org-10.1155-2017-7296467

Case Report

Department of Otolaryngology, Head and Neck Surgery, King Faisal Specialist Hospital and Research Centre, MBC 47, P.O. Box 3354, Riyadh 11211, Saudi Arabia

Department of Pathology, King Faisal Specialist Hospital and Research Centre, P.O. Box 3354, Riyadh 11211, Saudi Arabia

Correspondence should be addressed to Sarah S. Al-Otaibi

Received 6 January 2017; Revised 1 April 2017; Accepted 19 April 2017; Published 14 May 2017

Academic Editor: Abrão Rapoport

Copyright © 2017 Sarah S. Al-Otaibi et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Acinic cell carcinoma with high-grade transformation of the salivary gland is an unusual variant with less than fifty cases being reported in the literature. It is characterized by a low- and high-grade component juxtaposed with one another and tends to take on a more aggressive clinical course than its low-grade counterpart, suggesting a poor clinical outcome. We, hereby, report a case of acinic cell carcinoma in a 48-year-old woman with a 6-month history of a right parotid facial swelling rapidly increasing in size. The tumor was initially resected; however, residual focal tissue subsequently revealed areas typical of low-grade acinic cell carcinoma as well as high-grade transformation-dedifferentiation via histopathology.





Autor: Sarah S. Al-Otaibi, Faiza Alotaibi, Yaseer Al Zaher, Nabil Al Zaher, and M. A. Dababo

Fuente: https://www.hindawi.com/



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