Malakoplakia of the Pancreas with Simultaneous Colon Involvement: Case Report and Review of the LiteratureReport as inadecuate

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Case Reports in Pathology - Volume 2015 2015, Article ID 649136, 5 pages -

Case ReportGeisinger Medical Center, 100 North Academy Avenue, Danville, PA 17821, USA

Received 23 March 2015; Accepted 11 May 2015

Academic Editor: Katsuyuki Aozasa

Copyright © 2015 Surya Guha and Haiyan Liu. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Although malakoplakia has been reported to occur at various body sites, pancreatic malakoplakia with simultaneous colonic involvement is very rare. Lesions of malakoplakia can masquerade as tumor masses leading to unwanted resections. Nevertheless, malakoplakia can occur in association with frank carcinomas, especially in the colon. By reporting a case of pancreatic malakoplakia diagnosed by fine needle aspiration cytology, this paper aims to describe cytologic features of malakoplakia and to further review findings from previous reported cases of pancreatic malakoplakia in the literature. With advances in minimally invasive, image-guided aspiration technologies, cytomorphological analyses can diagnose lesions of malakoplakia. This may help avoid surgeries that would have otherwise been carried out due to a misleading impression of tumor. However challenges remain as to the further management of patients diagnosed with this condition. More studies are necessary to determine the probability of malignancies arising in association with malakoplakia, in order to devise appropriate treatment protocols.

Author: Surya Guha and Haiyan Liu



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