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International Journal of HepatologyVolume 2012 2012, Article ID 357687, 17 pages

Research Article

Fraunhofer Institute for Medical Image Computing MEVIS, Universitätsallee 29, 28359 Bremen, Germany

School of Engineering and Science, Jacobs University, Campus Ring 1, 28759 Bremen, Germany

Received 5 April 2012; Accepted 16 May 2012

Academic Editor: Mathieu Vinken

Copyright © 2012 Lars Ole Schwen and Tobias Preusser. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


A proper geometric model of the vascular systems in the liver is crucial for modeling blood flow, the connection between the organ and the rest of the organism. In vivo imaging does not provide sufficient details, so an algorithmic concept for extending measured vascular tree data is needed such that geometrically realistic structures can be generated. We develop a quantification of similarity in terms of different geometric features. This involves topological Strahler ordering of the vascular trees, statistical testing, and averaging. Invariant features are identified in human clinical in vivo CT scans. Results of the existing -Constrained Constructive Optimization- algorithm are compared to real vascular tree data. To improve bifurcation angles in the algorithmic results, we implement a postprocessing step calibrated to the measured features. This framework is finally applied to generate realistic additional details in a patient-specific hepatic vascular tree data set.

Autor: Lars Ole Schwen and Tobias Preusser



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