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Journal of Chemistry - Volume 2015 2015, Article ID 525832, 12 pages -

Review Article

Department of Biochemistry, Faculty of Dentistry, University of Medicine and Pharmacy Carol Davila, 050474 Bucharest, Romania

Biochemistry-Proteomics Department, “Victor Babes” National Institute of Pathology, No. 99 101, Splaiul Independentei, Sector 5, 050096 Bucharest, Romania

Faculty of Medicine, Titu Maiorescu University, Strada Dâmbovnicului 22, 040441 Bucharest, Romania

Agricultural and Biological Engineering Department, Louisiana State University and LSU Ag Center, 149 EB Doran Building, Baton Rouge, LA 70803, USA

Department of Physiology, “Carol Davila” University of Medicine and Pharmacy, 050474 Bucharest, Romania

Received 8 December 2014; Revised 9 February 2015; Accepted 11 February 2015

Academic Editor: Dennis Douroumis

Copyright © 2015 Maria Justina Roxana Virlan et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Polylactic-co-glycolic acid or PLGA is a biodegradable polymer used in a wide range of medical applications. Specifically PLGA materials are also developed for the dental field in the form of scaffolds, films, membranes, microparticles, or nanoparticles. PLGA membranes have been studied with promising results, either alone or combined with other materials in bone healing procedures. PLGA scaffolds have been used to regenerate damaged tissues together with stem cell-based therapy. There is solid evidence that the development of PLGA microparticles and nanoparticles may be beneficial to a wide range of dental fields such as endodontic therapy, dental caries, dental surgery, dental implants, or periodontology. The aim of the current paper was to review the recent advances in PLGA materials and their potential uses in the dental field.

Autor: Maria Justina Roxana Virlan, Daniela Miricescu, Alexandra Totan, Maria Greabu, Cristiana Tanase, Cristina M. Sabliov, Consta



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