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International Journal of DentistryVolume 2013 2013, Article ID 312747, 8 pages

Research Article

Department of Biomedical Sciences, University of Padova, Via G. Colombo 3, 35100 Padova, Italy

Department of Neurosciences, University of Padova, Via Venezia 90, 35100 Padova, Italy

CNR-IDPA c-o Department of Environmental Sciences Informatics and Statistics, Universita Ca’ Foscari, Dorsoduro 2137, 30123 Venezia, Italy

Received 14 May 2013; Revised 10 July 2013; Accepted 31 July 2013

Academic Editor: Ryo Jimbo

Copyright © 2013 Eriberto Bressan et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Nanotechnology has gone through a period of rapid growth, thus leading to the constant increase in the application of engineered nanomaterials in daily life. Several different types of nanoparticles have been engineered to be employed in a wide array of applications due to their high surface to volume ratio that leads to unique physical and chemical properties. So far, silver nanoparticles AgNps have been used in many more different medical devices than any other nanomaterial, mainly due to their antimicrobial properties. Despite the promising advantages posed by using AgNps in medical applications, the possible health effects associated with the inevitable human exposure to AgNps have raised concerns as to their use since a clear understanding of their specific interaction with biological systems has not been attained yet. In light of such consideration, aim of the present work is the morphological analysis of the intracellular behavior of AgNps with a diameter of 10 nm, with a special attention to their interaction with mitochondria.

Autor: Eriberto Bressan, Letizia Ferroni, Chiara Gardin, Chiara Rigo, Michele Stocchero, Vincenzo Vindigni, Warren Cairns, and Bar



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