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Croatian medical journal, Vol.55 No.4 August 2014. -

Cerebrospinal fluid CSF overproduction results from either

CSF infection or choroid plexus hypertrophy or tumor,

with only a single idiopathic case described so far.

We report a unique case of a male infant with Crouzon

syndrome who presented with intracranial hypertension,

caused by up to 4-fold increase in CSF daily production.

Conditions related to CSF overproduction, namely central

nervous system infections and choroid plexus hypertrophy

or tumor, were ruled out by repeated magnetic resonance

imaging and CSF samples. Medical therapy failed to reduce

CSF production and the patient underwent several shunting

procedures, cranial expansion, and endoscopic coagulation

of the choroid plexus. This article thoroughly reviews

pertinent literature on CSF production mechanisms and

possible therapeutic implications.



Autor: Gianluca Trevisi - ; Pediatric Neurosurgery, Catholic University Medical School, Rome, Italy Paolo Frassanito - ; Pediatric Neuro

Fuente: http://hrcak.srce.hr/



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