Congenital Cataract: Prevalence and Surgery Age at Zhongshan Ophthalmic Center ZOCReport as inadecuate

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Congenital cataract CC is the primary cause of treatable childhood blindness. Population-based assessments of prevalence and surgery age of CC, which are critical for improving management strategies, have been unavailable in China until now. We conducted a hospital-based, cross-sectional study of the hospital charts of CC patients younger than 18 years old from January 2005 to December 2010 at Zhongshan Ophthalmic Center ZOC in Guangzhou, China. Residence, gender, age at surgery, hospitalization time, and the presence of other ocular abnormalities were extracted and statistically analyzed in different subgroups. The search identified 1314 patients diagnosed with CC from a total of 136154 hospitalizations, which accounted for 2.39% of all the cataract in-patients and 1.06% of the total in-patients over the six-year study period. Of the identified CC patients, 9.2% had ≥2 hospitalizations due to the necessity of additional surgeries, with a total ratio of boys to girls of 1.75∶1. Based on a subgroup analysis according to age, patients 2–6 years old constituted the highest proportion 29.22% of all hospitalized CC patients, and those 13–18 years old constituted the lowest proportion 13.47% of the total number. The average age at surgery was 27.62±23.36 months, but CC patients ≤6 years old especially ≤6 months old became increasingly prevalent throughout the 6-year study period. A total of 276 cases 20.93% of CC were associated with one or more other ocular abnormalities, the highest incidence rates were observed for exotropia 6.24%, nystagmus 6.16%, and refractive error 3.65%. In conclusion, CC patients accounted for 2.39% of all cataract in-patients in a review of 6 years of hospitalization charts from ZOC. The age at the time of surgery decreased over the 6-year study period, which probably reflects the continuing improvement of public awareness of children’s eye care in China.

Author: Haotian Lin, Ye Yang, Jingjing Chen, Xiaojian Zhong, Zhaochuan Liu, Zhuoling Lin, Wan Chen, Lixia Luo, Bo Qu, Xinyu Zhang, Danyin



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