Ocular Complications in Cutaneous Lupus Erythematosus: A Systematic Review with a Meta-Analysis of Reported CasesReportar como inadecuado




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Journal of Ophthalmology - Volume 2015 2015, Article ID 254260, 8 pages -

Review ArticleDepartment of Ophthalmology, Sapienza University, Umberto I Hospital, Viale del Policlinico 155, 00186 Rome, Italy

Received 9 March 2015; Accepted 15 April 2015

Academic Editor: Enrique Mencía-Gutiérrez

Copyright © 2015 L. Arrico et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Ocular complications associated with cutaneous lupus erythematosus CLE are less studied compared with those ones associated with systemic lupus erythematosus SLE. The main ocular sites involved in patients affected by discoid lupus erythematosus DLE are eyelids followed by orbit and periorbit, the least being cornea. The most common complications are blepharitis usually affecting the lower lid and associated with some type of lid lesion such as plaque or erythematosus patches and madarosis. Few cases with LE profundus LEP and ocular complications are reported, but they are associated with orbital inflammatory syndrome and severe complications. The main treatment prescribed is hydroxychloroquine with a dose of 200 mg twice a day for 6 to 8 weeks. Corticosteroids are also used. Intervals between the correct diagnosis and the beginning of the ocular symptoms are commonly delayed. Ophthalmologist should be aware of the ocular manifestation of this autoimmune disease.





Autor: L. Arrico, A. Abbouda, I. Abicca, and R. Malagola

Fuente: https://www.hindawi.com/



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