Green Synthesis Methods of CoFe2O4 and Ag-CoFe2O4 Nanoparticles Using Hibiscus Extracts and Their Antimicrobial PotentialReportar como inadecuado

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Journal of Nanomaterials - Volume 2016 2016, Article ID 2106756, 12 pages -

Research Article

Ilie Murgulescu Institute of Physical Chemistry, Romanian Academy, 202 Splaiul Independentei, 060021 Bucharest, Romania

National Institute for Chemical Pharmaceutical Research and Development, 112 Calea Vitan, 031299 Bucharest, Romania

Microbiology Department, Faculty of Biology, University of Bucharest and Life, Environmental and Earth Sciences Division, Research Institute of the University of Bucharest ICUB, 91-95 Splaiul Independentei, Bucharest, Romania

Received 18 August 2016; Revised 12 October 2016; Accepted 23 October 2016

Academic Editor: Mohamed Bououdina

Copyright © 2016 Dana Gingasu et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


The cobalt ferrite CoFe2O4 and silver-cobalt ferrite Ag-CoFe2O4 nanoparticles were obtained through self-combustion and wet ferritization methods using aqueous extracts of Hibiscus rosa-sinensis flower and leaf. X-ray diffraction, scanning electron microscopy, Fourier transform infrared spectroscopy, and magnetic measurements were used for the characterization of the obtained oxide powders. The antimicrobial activity of the cobalt ferrite and silver-cobalt ferrite nanoparticles against Gram-positive and Gram-negative bacteria, as well as fungal strains, was investigated by qualitative and quantitative assays. The most active proved to be the Ag-CoFe2O4 nanoparticles, particularly those obtained through self-combustion using hibiscus leaf extract, which exhibited very low minimal inhibitory concentration values 0.031–0.062 mg-mL against all tested microbial strains, suggesting their potential for the development of novel antimicrobial agents.

Autor: Dana Gingasu, Ioana Mindru, Luminita Patron, Jose Maria Calderon-Moreno, Oana Catalina Mocioiu, Silviu Preda, Nicolae Stanic



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