Sexual Transmission of HCV in Heterologous Monogamous SpousesReport as inadecuate

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Journal of Sexually Transmitted Diseases - Volume 2014 2014, Article ID 140640, 2 pages -

Research Article

Clinical and Chemical Pathology Department, Faculty of Medicine, Ain Shams University, Cairo 11566, Egypt

General Medicine & Gastroenterology Department, Faculty of Medicine, Ain Shams University, Abbassia Square, Cairo 11566, Egypt

Received 13 July 2014; Revised 29 September 2014; Accepted 30 October 2014; Published 24 November 2014

Academic Editor: David Smajs

Copyright © 2014 Mona M. Rafik et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


We screened for evidence of HCV infection in healthy heterologous monogamous spouses of chronic HCV patients and studied the relation with various risk factors. A cross-sectional study of fifty healthy monogamous heterosexual spouses of HCV-positive index cases was carried out. All participants were HBV and HIV negative. The association with various risk factors was studied. Five spouses 10% showed evidence of HCV infection. Two partners were positive for HCV antibody alone 4% and 3 for antibody and HCV PCR 6%. No association was found between HCV infection and various sociodemographic parameters with the exception of older age categories. Intraspousal transmission of HCV may be an important source of spread of HCV infection. The reservoir of HCV-infected individuals in Egypt is sizable, and sexual transmission of HCV may contribute to the total burden of infection in Egypt.

Author: Mona M. Rafik, Yehia El Shazly, Amal A. Abbas, Walid Abd Elhady, Dina Ragab, and Dina AlShennawy



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