Epidemiologic Aspects of Atrial Fibrillation in a Tertiary Hospital in a Sub-Saharan Africa SettingReportar como inadecuado

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Background:Atrial fibrillation AF is the most frequent sustainedarrhythmia. The prevalence is increasing with that of other cardiovascular riskfactors in our low-income setting. It is potentially serious due to theassociated complications. Few data exist on the epidemiology of AF inSub-Saharan Africa SSA. Methodology: We carried out a cross-sectional studybetween 2005 and 2009 in the Cardiology Unit of the Douala General Hospital.Patients were adults ≥ 18 years of both sex, who had an ECG diagnosis of AtrialFibrillation and a comprehensive investigation of the cause of AF. Results: Atotal of 2581 patients were seen in this unit, of whom 182 7.1%, 95%: 6.1-8.1 had AF. Their mean age was 59.2 ± 15.4 years,and there were 100 58.2%, 95% CI: 51-65.6, p = 0.002 females. Hypertension was the most frequent risk factor77.3%, 95% CI: 70.3-82.8, and 163 95.3%, 95% CI: 90.7-97.8 of thepatients were symptomatic. Hypertensive heart disease 45.6%, 95% CI: 38.3-53.1, idiopathic dilated cardiomyopathy 19.3%, 95% CI: 14.1-25.9, andvalvular heart disease 16.4%, 95% CI: 11.6-22.6 were the main etiologicfactors of AF. The most frequent complications were heart failure seen in 7745%, 37.8-52.5 and ischemic stroke in 27 15.5%, 95% CI: 11.1 - 22 ofpatients. Digoxine was prescribed in 121 70.8%, 95% CI: 63.6-77.1 patientsto control heart rate, while amiodarone was prescribed in 67 29.2%, 95% CI:32.2-46.7 patients to revert to sinus rhythm. No electrical cardioversionwas carried out. Aspirine was prescribed in 119 69.6%, 95% CI: 62.3-76patients, and anti-vitamin K in 53 30.4%, 95% CI: 24.5-38.3 patients. Conclusion:Atrial fibrillation was seen in seven percent of patients in the Cardiology Unit of this low-income setting.Patients were relatively young compared with high income settings. Hypertension, idiopathicdilated cardiomyopathy, and valvular heart disease were the main causes. Ratecontrol was the main treatment strategy. Oral anti-coagulants were lessfrequently used.


Epidemiology, Atrial Fibrillation, Cameroon, Sub-Saharan Africa

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Kamdem, F. , Hamadou, B. , Kamdem, M. , Nganou, C. , Dzudie, A. , Monkam, Y. and Kingue, S. 2017 Epidemiologic Aspects of Atrial Fibrillation in a Tertiary Hospital in a Sub-Saharan Africa Setting. Open Access Library Journal, 4, 1-8. doi: 10.4236-oalib.1103384.

Autor: Félicité Kamdem1,2, Ba Hamadou3,4, Marius Kamdem2, Christ Nadège Nganou3,4, Anastase Dzudie2,3, Yves Monkam2, Samuel Kingue3,5

Fuente: http://www.scirp.org/


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