Hepatitis A Antibody Seroprevalence in a Selected Kenyan Pediatric PopulationReportar como inadecuado




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Theincidence of infection by Hepatitis A virus shows regional variation being highestin developing countries. Determination of age specific Hepatitis A virus HAV seroprevalenceand the associated risk factors would help better plan for national preventivestrategies including vaccination. We carried out a cross-sectional study on 300children from Nairobi city, Kenya during the years 2003-2004. The age range of the children was 2 - 14 years and were from low and highsocioeconomic status SES families. The indicators of SES included employmentstatus, residence, number of children per patient’s household, parents’ levelof education and source of drinking water. SES was encoded and analysed using StatisticalProgram for Social Sciences SSPS version 16.0. Seroprevalence of HAV antibodies was significantly higher amongchildren of low SES, 77.6% by the age of 14 years compared to children of highSES, 38.9% by the same age. Crowded household and parental education weresignificantly associated with high seropositivity and seronegativityrespectively. There is significant rate of amongst the studied population especially those fromricher backgrounds making them more susceptible to severe infection in futurewith concomitant complications. We propose that revision of nationalvaccination program should be considered to include Hepatitis A vaccination.

KEYWORDS

Seroprevalence, Hepatitis A, Pediatrics

Cite this paper

Wasunna, A. , Murila, F. , Obimbo, M. , Rama, M. and Musembi, H. 2016 Hepatitis A Antibody Seroprevalence in a Selected Kenyan Pediatric Population. Open Journal of Pediatrics, 6, 316-323. doi: 10.4236-ojped.2016.64043.





Autor: Aggrey Wasunna1*, Florence Murila1, Moses M. Obimbo2, Mwaswere J. Rama3, Horatius Musembi4

Fuente: http://www.scirp.org/



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