Tuberculin as Intralesional Therapy for Viral Warts—Single-Blind, Split, Placebo, Controlled StudyReportar como inadecuado




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Background:BCG vaccine as an antigen has proved its effectiveness as an immunotherapy for viralwarts. Tuberculin is an antigenic extract of M. tuberculosis capable of eliciting an immunological skin reaction.Objective: To assess the efficacy of tuberculin intralesional injection in the treatmentof viral warts. Patients and Methods: Scoring of response to treatment was as follow: 1 Responders:including patients who showed complete cure or those with good response >50%reduction. 2 Non responders: including patients who showed minimal response 15patients showed no response, 1 patient showed minimal response, 7 patients showedgood response and 7 patients showed complete cure 23.33%. Regarding the lesionstreated with intralesional distilled water, 25 patients showed no response, 3 patientsshowed minimal response, 26.66 patients showed good response and no patient showedcomplete cure of their warts. Of the 14 responder patients to intralesional tuberculin,10 patients were tuberculin tested positive, and 4 patients were tested negative,and of the 16 non responder patients to intralesional tuberculin, 3 patients weretuberculin tested positive, and 13 patients were tuberculin tested negative whichwas statistically No side effectsreported from tuberculin therapy apart from mild pain at site of injection. Conclusion:Intralesional injection of tuberculin is an effective therapy for viral warts



Autor: Khalifa E. Sharquie1,2*, Jamal R. Al-Rawi3, Adil A. Noaimi1,2, Wael H. Majly4

Fuente: http://www.scirp.org/



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