A Review of Structure Activity Relationship of Amiodarone and Its DerivativesReportar como inadecuado




A Review of Structure Activity Relationship of Amiodarone and Its Derivatives - Descarga este documento en PDF. Documentación en PDF para descargar gratis. Disponible también para leer online.

Structure Activity Relationship forms the basis of Rational Drug Design in the circles of pharmaceutical and medicinal chemistry. Appropriate knowledge of functional outcomes of structural modifications is crucial in conferring desired pharmacological properties to a chemical compound. Amiodarone is a classical antiarrythmic agent with a long list of adverse effects. This article attempts to review the structure activity relationship of some of the homologues of amiodarone in order to determine the most clinically desirable molecule.

KEYWORDS

Amiodarone, Dronedarone, Structure-Activity-Relationship

Cite this paper

Siddiqui, M. , Khan, A. and Zaka, M. 2016 A Review of Structure Activity Relationship of Amiodarone and Its Derivatives. Open Journal of Medicinal Chemistry, 6, 37-42. doi: 10.4236-ojmc.2016.62003.





Autor: Moiz A. Siddiqui1, Amjad Khan2,3*, Mehreen Zaka3

Fuente: http://www.scirp.org/



DESCARGAR PDF




Documentos relacionados