Assessment of Antiretroviral Efficacy of the Medicinal Synthetic Aluminum-Magnesium Silicate {Al4SiO43 3Mg2SiO4 → 2Al2Mg3SiO43}Reportar como inadecuado




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HIV-AIDS patients were treated, daily, withMSAMS 50 mg-kg, MSAMS-stabilized Ampicillin trihydrate 7.5 mg-kg andimmunace extra-protectionM? 1 tablet, for one month and then, with only MSAMSand the immune stimulants. They were tested, monthly, for viral loads and CD4-lymphocytes counts. Those whose viral loads became undetectable were tested forHIV confirmation antigens-antibody. Their mean-viral load increased P =0.020 from 1820.30 ± 868.75 to 2855.90 ± 960.98 after first month, before reducingP = 0.0.030 to: 1565.20 ± 743.17; 759.20 ± 473.65; 345.50 ± 115.01; 192.80 ±97.40; 95.00 ± 55.80; 37.40 ± 26.46; 17.50 ± 16.88 undetectable. Theirmean-CD4 count was 496.80 ± 194.39 lymphopenia. It reduced P = 0.008 to263.90 ± 149.26 after first month, before increasing P = 0.001 to: 507.90 ±133.19; 692.70 ± 113.34; 840.20 ± 139.41; 1007.30 ± 163.50; 1537.10 ± 302.10;1924.60 ± 247.45; 2707.00 ± 837.87 lymphocytosis. Patients whose viral loadsbecame undetectable tested HIV-negative, one month after. CD4-lymphocytescount, approximating to zero-viral load, calculated from equation Y = 2297.80 - 1.4731X of line of best fit of graph of their viral loads onCD4-lymphocytescounts, was 1559.84-ml.

KEYWORDS

HIV, MSAMS-Nanoparticles, Opposite Electrical Charges, HIV-Positive, Lymphopenia, HIV-Antigens-Antibody Negative, Lymphocytosis

Cite this paper

Ezeibe, M. , Aleeyu, D. , Aneke, N. , Obarezi, T. , Ogbonna, I. and Kalu, E. 2016 Assessment of Antiretroviral Efficacy of the Medicinal Synthetic Aluminum-Magnesium Silicate {Al4SiO43 + 3Mg2SiO4 → 2Al2Mg3SiO43}. World Journal of AIDS, 6, 74-80. doi: 10.4236-wja.2016.62011.





Autor: Maduike C. O. Ezeibe1, Dahiru Aleeyu2, Nnaemeka K. Aneke3, Thompson N. Obarezi3, Ijeoma J. Ogbonna1, Ekenma Kalu1

Fuente: http://www.scirp.org/



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