Therapeutic Potential of Neem Synthesized Silver Nanoparticles on Human Gastric Cancer Cells in VitroReportar como inadecuado




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Nanotechnology has shown significant promise in development of drugs and drug delivery systems that can overcome all limitations and address urgent needs to improve efficacy of diagnosis and therapy of various diseases including cancer. The functionalization with neem compounds as synthesis and capping agent had shown very high anticancer activities against Gastric cancer cells in vitro. The biochemical factors like albumin, glucose, and DNA concentrations were modulated along with Protease inhibitor and Catalase activates, the various cancer specific proteins like p53, GRD 70 - 78 kDa and other proteins of sizes 35 - 40 kDa corresponding to H+K+ATPase protein etc. The apoptic activity and antiproliferative activity were demonstrated with Gastric cancer cells in vitro.

KEYWORDS

Gastric Cancer, Nanotherapy, Silver Nanoparticles, Neem Compounds, iIn Vitroi Cancer Treatment, Biochemical Changes in Nanotreatment

Cite this paper

Sironmani, T. 2016 Therapeutic Potential of Neem Synthesized Silver Nanoparticles on Human Gastric Cancer Cells in Vitro. World Journal of Nano Science and Engineering, 6, 90-110. doi: 10.4236-wjnse.2016.62010.





Autor: T. Anitha Sironmani

Fuente: http://www.scirp.org/



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