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Although intensive interventions with lowcarbohydrate diets compared with higher carbohydrate diets can reduce HbA1c inpeople with type 2 diabetes, it is not clear if simple advice to make modestreductions in carbohydrate is effective in clinical practice. Forty-threepeople with type 2 diabetes and poor control HbA1c > 7.5% were randomizedto receive 2 short education sessions over 6 months with a non-dietitianresearcher on how to reduce carbohydrate intake by about 25% or to 2 controlsessions in which the Australian Guide to Healthy Eating was provided. Hba1cand fasting glucose and lipids were measured at baseline and 3 months and 6months. 33 volunteers attended a baseline visit; 27 completed 3 months and 24 6months. HbA1c was reduced by 0.6% - 0.7% in the low carbohydrate diet groupcompared with the control group P = 0.1. Fasting glucose was reduced by 2.3mmol-L compared with the control group at 3 months P < 0.03 only. Changesin HbA1c at 6 months were related to baseline HbA1c in the intervention grouponly. Although we have obtained suggestive evidence that a low carbohydratediet can be successfully implemented in normal practice without professionalhelp, our results are limited by low participant numbers and further studiesare required.


Translational Study, Low Carbohydrate Diet, HbA1c, Fasting Glucose

Cite this paper

Clifton, P. , Coles, L. and Galbraith, C. 2016 Low Carbohydrate Diets in Type 2 Diabetes—A Translational Study. Journal of Diabetes Mellitus, 6, 152-157. doi: 10.4236-jdm.2016.62016.

Author: Peter M. Clifton1,2*, Leah T. Coles2, Clare E. Galbraith2

Source: http://www.scirp.org/


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