Levels, Trends and Inter-Regional Variations in Transfusion Transmissible Infection Positivity among Blood Donors in India: Evidence from India’s National HIV ProgramReportar como inadecuado




Levels, Trends and Inter-Regional Variations in Transfusion Transmissible Infection Positivity among Blood Donors in India: Evidence from India’s National HIV Program - Descarga este documento en PDF. Documentación en PDF para descargar gratis. Disponible también para leer online.

In India, transfusion transmissibleinfections TTIs are monitored for trends at the blood bank level, but limitedefforts have been made to analyze data from a large number of blood banks andpresent it at the national, regional and state levels. The ComputerizedManagement Information System CMIS, National AIDS Control Organization’sNACO online data capturing system, systematically collects information onTTIs in a monthly aggregated format from blood banks across the country. Thisinformation is being captured in NACO’s annual reports, but a systematicscientific analysis and publication of the same have not been attempted so far.Hence, the objective of this study is to analyze and report TTIs among blooddonors in India at three different levels—national, regional and state—from497 consistent blood banks reporting through CMIS during 2008-2012. Nationallevel analysis shows an increasing trend in voluntary blood donation from 9.28lakh to 19.02 lakh, and a decreasing trend in TTIs, with female donorsconstituting only 6% of the entire pool of donors. Of the five TTIs studied, in2012 Hepatitis-B-surface Antigen HBsAg positivity was highest 0.9%,followed by Hepatitis C Virus HCV 0.45%, syphilis 0.23%, HIV 0.17% andmalaria 0.03%. Regional analysis indicated that voluntary donation was highin the Eastern and Western regions, with 11% of female donors in Eastern Indiain 2012. All the TTIs showed a declining trend, except HCV, which showed arising trend in the Eastern and Southern regions. The level of positivity forall the five TTIs was higher than the national average in the Eastern region.Among the TTIs, HIV positivity among voluntary donors was below the nationalaverage, while in Mizoram both HBsAg and HCV of more than 1% seropositivityand VDRL of 1.7% in Arunachal Pradesh had been reported. Malaria has the lowestnational positivity, with Nagaland reporting a high positivity of 0.4%.Although the national and regional trends in TTI positivity are declining,regional level variations in TTIs, especially in hepatitis, suggest theimportance of advocating for pre-donation counseling and educating donors onself-exclusion.

KEYWORDS

HIV, Hepatitis, Transfusion Transmissible Infections, CMIS, Female Donors, India

Cite this paper

Sakthivel, S. , Yujwal Raj, P. , Mishra, S. and Sharma, A. 2015 Levels, Trends and Inter-Regional Variations in Transfusion Transmissible Infection Positivity among Blood Donors in India: Evidence from India’s National HIV Program. World Journal of AIDS, 5, 217-225. doi: 10.4236-wja.2015.53025.





Autor: Saravanamaurthy P. Sakthivel1, Pinnamaneni Yujwal Raj2, Shanoo Mishra3, Arun Kumar Sharma4

Fuente: http://www.scirp.org/



DESCARGAR PDF




Documentos relacionados