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Anticancer antibiotics have made a successful impact in the field of chemotherapeutics.For most of them, DNA is the molecular target. Some act as DNA intercalators orsome prevent DNA repair among other mechanismsof actions, they are seen to have. The major disadvantages of these drugsthough are the constant side effects and toxicities. With more focus on discoveryof new drugs with newer scaffolds, the urge to discover and modify anticancer antibioticsis being lost. Modifications or even the wider research can yield newer better drugsfor clinical use. The review here discusses the current antibiotic therapeutics,newer discoveries in the field as well ideas for future research.

KEYWORDS

Antibiotics, Lactams, Cancer, Mechanism of Action

Cite this paper

Bhattacharya, B. and Mukherjee, S. 2015 Cancer Therapy Using Antibiotics. Journal of Cancer Therapy, 6, 849-858. doi: 10.4236-jct.2015.610093.





Autor: Biplob Bhattacharya1*, Sreya Mukherjee2

Fuente: http://www.scirp.org/



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