Left Atrial Systolic and Diastolic Dysfunction in Patients with Chronic Constrictive Pericarditis: A Study Using Speckle Tracking and Conventional EchocardiographyReportar como inadecuado




Left Atrial Systolic and Diastolic Dysfunction in Patients with Chronic Constrictive Pericarditis: A Study Using Speckle Tracking and Conventional Echocardiography - Descarga este documento en PDF. Documentación en PDF para descargar gratis. Disponible también para leer online.

Background

Left atrial LA function plays an important role in the maintenance of cardiac output, however, in patients with constrictive pericarditis CP, whether pericardial restriction and adhesion can lead to LA dysfunction, and the characteristics of LA function remain unclear. The aim of the study is to compare the left atrial LA function of patients with CP to that of healthy study participants using speckle tracking echocardiography STE and conventional echocardiography.

Methods and Results

Thirty patients with CP and 30 healthy volunteers controls were enrolled in the study. The underlying cause of CP was viral pericarditis in 24 80% patients and unknown in 6 20% patients. The LA maximum volume Vmax, LA minimal volume Vmin, and LA volume before atrial contraction Vpre-a were measured using biplane modified Simpson’s method. The LA expansion index LA reservoir function was determined as follows: LAVmax - LAVmin-LAVmin ×100. The passive emptying index LA conduit function was calculated as follows: LAVmax - LAVpre-a-LAVmax ×100, and the active emptying index booster pump function was calculated as follows: LAVpre-a - LAVmin-LAVpre-a ×100. All the patients underwent two-dimensional STE. The LA global systolic strain S, systolic strain rate SrS, early diastolic strain rate SrE and late diastolic strain rate SrA were measured. The LA expansion index, passive emptying index, the active emptying index and the LA global S, SrS, SrE, SrA were found to be significantly lower in patients with CP than in the control participants P <0.001. LA function was correlated with the early diastolic velocity of the lateral mitral annulus P <0.05.

Conclusions

Although left ventricular systolic function was preserved in patients with CP, the LA reservoir, conduit, and booster functions were impaired. Pericardial restriction and impairment of the LA myocardium may play an important role in the reduction of LA function in patients with CP.



Autor: Shuang Liu, Chunyan Ma, Weidong Ren , Jun Yang, Yan Zhang, Sha Li, Yanbin Cheng

Fuente: http://plos.srce.hr/



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