Job Strain and Cardiovascular Disease Risk Factors: Meta-Analysis of Individual-Participant Data from 47,000 Men and WomenReportar como inadecuado




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Background

Job strain is associated with an increased coronary heart disease risk, but few large-scale studies have examined the relationship of this psychosocial characteristic with the biological risk factors that potentially mediate the job strain – heart disease association.

Methodology and Principal Findings

We pooled cross-sectional, individual-level data from eight studies comprising 47,045 participants to investigate the association between job strain and the following cardiovascular disease risk factors: diabetes, blood pressure, pulse pressure, lipid fractions, smoking, alcohol consumption, physical inactivity, obesity, and overall cardiovascular disease risk as indexed by the Framingham Risk Score. In age-, sex-, and socioeconomic status-adjusted analyses, compared to those without job strain, people with job strain were more likely to have diabetes odds ratio 1.29; 95% CI: 1.11–1.51, to smoke 1.14; 1.08–1.20, to be physically inactive 1.34; 1.26–1.41, and to be obese 1.12; 1.04–1.20. The association between job strain and elevated Framingham risk score 1.13; 1.03–1.25 was attributable to the higher prevalence of diabetes, smoking and physical inactivity among those reporting job strain.

Conclusions

In this meta-analysis of work-related stress and cardiovascular disease risk factors, job strain was linked to adverse lifestyle and diabetes. No association was observed between job strain, clinic blood pressure or blood lipids.



Autor: Solja T. Nyberg , Eleonor I. Fransson, Katriina Heikkilä, Lars Alfredsson, Annalisa Casini, Els Clays, Dirk De Bacquer, Nico Dra

Fuente: http://plos.srce.hr/



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