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The COPD AssessmentTest was recently developed to assess health status in patients with COPD. However,little was known about its application to patients with interstitial lungdisease, so we examined the relationship between the COPD Assessment Test scoreand respiratory impairment including the clinical picture in subjects withinterstitial lung disease. Data were collected retrospectively from 52 consecutivesubjects with interstitial lung disease on admission to our facility. Allsubjects completed the COPD Assessment Test, in which a higher score representeda worse health status. They were also assessed by pulmonary function test, SpO2 during 6-min walk test, and arterial blood gases. The COPD Assessment Testscore was negatively correlated with the percentage of predicted forced vitalcapacity, forced expiratory volume in 1 second, total lung capacity, diffusioncapacity of the lung for carbon monoxide, and PaO2 p = 0.0005, 0.005, 0.0002, 0.0005, and 0.002,respectively. Breathlessness was detected as the high scoring item, whilephlegm and sleep were the last affected items. The COPD Assessment Test scorewas higher in subjects with oxygen desaturation in SpO2 ≥4% during6-min walk test p = 0.0001 and insubjects on home oxygen therapy p = 0.0007.More than 75% of subjects with oxygen desaturation during walking wereclassified into a medium or severer impact level of the COPD Assessment Testscore, and subjects on home oxygen therapy were classified into a high orseverer impact level. PaCO2 in room air and SpO2 at restdid not correlate with the COPD Assessment Test score. The reliability of itemsin the COPD Assessment Test was 0.87 by Cronbach’s α coefficient. Our results suggest that the COPD Assessment Testmay be a candidate for evaluating the health status and impact of disease onpatients with interstitial lung disease.


Interstitial Lung Disease, Quality of Life, Questionnaire, Pulmonary Function, Oxygen Saturation, Home Oxygen Therapy

Cite this paper

Someya, F. and Nakagawa, T. 2014 Application of the COPD Assessment Test CAT to Patients with Interstitial Lung Disease. Health, 6, 2562-2569. doi: 10.4236-health.2014.619295.

Autor: Fujiko Someya*, Takao Nakagawa



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