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Introduction: Theincidence of ocular metastasis from Breast Carcinoma is only between 5% - 30%,mainly located in choroid, but the location in optic nerve is even moreinfrequent. We present a rare case that combined both locations sequentially inthe same eye. Methods: Case report. Results: A 58-year-old woman with advancedbreast cancer was referred with a choroidal metastasis in her right eye whichresponded well to systemic Taxol and Avastin. Afterwards, she developed anoptic nerve metastasis in the same eye when she was under the treatment, so itwas changed to Docetaxel. Unfortunately the patient didn’t respond to thistreatment and died. Conclusions: Choroidal metastasis secondary to breastcancer generally responds well to radiotherapy. Even so, in cases that a greatdeterioration of visual acuity is expected after radiation, chemotherapy liketaxanes is an alternative to preserve vision with complete tumor regression.Nevertheless, the presentation of a second metastasis in optic nerve can beindicative of inadequate treatment of metastatic disease or complication of thetreatment, or both.



KEYWORDS

Choroidal Metastasis, Optic Nerve Metastasis, Breast Cancer, Hormone Therapy, Taxanes

Cite this paper

Asencio-Duran, M. , Vallejo-Garcia, J. , Rodriguez-Rodriguez, I. , Sánchez-Orgaz, M. and Arbizu-Duralde, Á. 2014 Optic Nerve Metastasis from Breast Carcinoma after Treatment with Taxanes. Case Reports in Clinical Medicine, 3, 336-339. doi: 10.4236-crcm.2014.36074.





Autor: Mónica Asencio-Duran, José-Luis Vallejo-Garcia, Isabel Rodriguez-Rodriguez, Margarita Sánchez-Orgaz, Álvaro Arbizu-Duralde

Fuente: http://www.scirp.org/



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