The Influence of Culture Medium Type on Cellular Phenotype of Canine Adipose Derived Stem Cells - Descarga este documento en PDF. Documentación en PDF para descargar gratis. Disponible también para leer online.

Canine adipose derived stem cells ASCs hold a great promise for thetherapy of osteoarthritis in veterinary medicine. Current therapy is anautologous, stromal vascular fraction. Allogeneic ASCs provide many advantages,including efficient, cost-effective treatments while eliminating a surgicalprocedure in a diseased animal. Cultured ASCs can be expanded andcharacterized, allowing selection of desirable qualities. Use of allogeneicASCs requires selection of a culture medium that provides consistent, desirablecellular products. The supplements within a medium can greatly influencecellular phenotypes. We hypothesized that medium type influenced cellularphenotype, allowing selection of a specified cellular product for clinical applications.We evaluated ASCs derived from adipose tissue of six dogs, assessing



KEYWORDS

Canine; Mesenchymal Stem Cells; Adipose-Derived Stromal Cells; Culture Conditions

Cite this paper

Kiefer, K. , Pluhar, G. , Conzemius, M. and O’Brien, T. 2014 The Influence of Culture Medium Type on Cellular Phenotype of Canine Adipose Derived Stem Cells. Open Journal of Regenerative Medicine, 3, 28-37. doi: 10.4236-ojrm.2014.31004.





Autor: Kristina M. Kiefer, G. Elizabeth Pluhar, Michael G. Conzemius, Timothy D. O’Brien

Fuente: http://www.scirp.org/

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