Local anaesthesia using Articaine and Lidocaine in oral and dental surgery: A comparative meta-analysisReportar como inadecuado




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Background: Articaine is anamide local anaesthetic, which is gaining popularity for use in dental and oralsurgical anaesthesia in the United Kingdom. Hitherto there has beeninsufficient evidence to recommend articaine above the more commonly usedlidocaine for dental procedures. The aim of this study is to compare theefficacy of 4% articaine with 1:100,000 adrenaline 4AA with that of 2%lidocaine with 1:100,000 adrenaline 2LA administered as buccal infiltrationsfor anaesthesia in mandibular permanent first molar teeth. Any significant advantagenoted may obviate the need for regional blockage of the inferior dental nervein dental or minor oral surgical procedure under local anaesthesia. Objectives:To review the published literature comparing the efficacies of 4AA and 2LAfor achieving pulpal anaesthesia in human mandibular permanent first molarteeth. Null Hypothesis: 4AA and 2LA are of equal efficacy when used toanaesthetize mandibular permanent first molar teeth by buccal infiltration. Method:An electronic search encompassing Ovid MEDLINE?, PubMed National Center forBiotechnology Information, US National Library of Medicine, SCOPUS?, SCIRUS?,EMBASE? databases and the Cochrane Library was performed to identify trialsrelating to the efficacy of 4AA and 2LA local anaesthetic solutions on mandibularfirst molars in adult participants. Study characteristics and outcome data wereextracted as a basis for meta-analysis. Results: Three randomised controlledtrials were identified for this meta-analysis. The relative efficacy of 4AA over2LA in anesthetizing permanent first mandibular molars was calculated at 1.5795% CI = 1.27 to 1.95. Conclusion: Despite the promising results shown in themeta-analysis it is difficult to say from the evidence presented that 4AAshould be used clinically in preference over 2LA.

KEYWORDS

Lidocaine; Articaine; Meta-Analysis

Cite this paper

Saggu, M. , Aga, H. , Saggu, J. and Burke, G. 2014 Local anaesthesia using Articaine and Lidocaine in oral and dental surgery: A comparative meta-analysis. Open Journal of Stomatology, 4, 84-91. doi: 10.4236-ojst.2014.42014.





Autor: M. K. Saggu, H. Aga, J. S. Saggu, G. A. E. Burke

Fuente: http://www.scirp.org/



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