IL-4, IL-6, IL-10, IL-17A and vascular endothelial growth factor in the vitreous of patients with proliferative diabetic retinopathyReportar como inadecuado




IL-4, IL-6, IL-10, IL-17A and vascular endothelial growth factor in the vitreous of patients with proliferative diabetic retinopathy - Descarga este documento en PDF. Documentación en PDF para descargar gratis. Disponible también para leer online.

In current article, results of the determination ofthe concentrations of vascular endothelial growth factor VEGF, and someinterleukins IL-4, IL-6, IL-10, IL-17А in the vitreous of patients withproliferative diabetic retinopathy are presented. We have found that in themechanism of development of diabetic retinopathy, significant role plays an activationof local inflammation process and vascular proliferation. This is evidenced bya significant increase in the vitreous concentration of IL-4, IL-6, IL-10,IL-17A and vascular endothelial growth factor. Identified correlations betweenVEGF and IL-17A, between VEGF and IL-4, and between IL-17A and IL-4 show therelationship of inflammation and proliferation processes in the pathogenesis ofdiabetic retinopathy.

KEYWORDS

Diabetic Retinopathy; Cytokines; Vascular Endothelial Growth Factor

Cite this paper

Chernykh, V. , Smirnov, E. , Varvarinsky, Y. , Chernykh, D. , Obukhovа, O. and Trunov, A. 2014 IL-4, IL-6, IL-10, IL-17A and vascular endothelial growth factor in the vitreous of patients with proliferative diabetic retinopathy. Advances in Bioscience and Biotechnology, 5, 184-187. doi: 10.4236-abb.2014.53023.





Autor: Valery Chernykh, Evgeny Smirnov, Yegor Varvarinsky, Dmitry Chernykh, Olga Obukhovа, Aleksandr Trunov

Fuente: http://www.scirp.org/



DESCARGAR PDF




Documentos relacionados