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Introduction: Acute blunt or open renal traumasometimes requires conservative measure which involvesthe use of specific materials in order to adequately restore renal parenchima.The purpose of this study is to analyze the effects of the sugar canebiopolymer sponge in an experimental model of renal trauma in rabbits. Methods: Experimental prospectivestudy was paired withtwelve New Zealand rabbits. After induction of renal trauma bilateralhigh-grade grade 4-collecting system, according to AAST, the sugar canebiopolymer sponge was used for homeostasis and reconstruction of the right renalparenchyma experimental group. The same procedure was performed in the left kidney,but using the Surgifoam? sponge Control Group. The animals weresacrificed after four weeks. Histological analysis was performed and theresults were compared afterstatistically being evaluated.Results: Comparing theexperimental group with the control, there was more inflammatory reaction andpremature adhesions in the first one. Concerning the influence on efficacy andbiocompatibility of the biopolymer, no serious complications like massive bleeding, haematoma, fistulaor urinary stone formation were found in both groups. Conclusion: The sugar cane biopolymer sponge demonstrated goodefficacy in relation to hemostatic control and reconstruction of the renalparenchyma without major complications. Future studies may direct its routineuse in urologic practice.

KEYWORDS

Acute Renal Injury; Surgical Hemostasis; Absorbable Implants; Inflammation; Biocompatible Materials

Cite this paper

L. Tavares, F. Vilar, J. Aguiar, A. Paz, F. Melo and G. Negromonte -Biopolymer Sponge for High Grade Renal Trauma: An Experimental Study in Rabbits,- Open Journal of Urology, Vol. 4 No. 1, 2014, pp. 1-6. doi: 10.4236-oju.2014.41001.





Autor: Leandro H. M. Tavares, Fábio O. Vilar, José L. Aguiar, Alexandre R. Paz, Francisco A. D. Melo, Gustavo R. P. Negromonte

Fuente: http://www.scirp.org/



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