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Objective:This multicenter clinical study was to assess the clinical usability of an oralmoisture-checking device in detecting the dry mouth patients and evaluating theoptimal measurement site. Materials and Methods: The study group comprised 250 patientswith dry mouth and 241 healthy volunteer subjects at 13 medical centers. This devicewas used to measure the moisture degrees of the lingual mucosa and the buccal mucosa.Subjective oral dryness, objective oral dryness, and saliva flow rates were alsocompared between the two groups. For statistical analysis, receiver-operating characteristic analysis was performed to calculate the area under the curve AUC. Results: The moisture degree ofthe lingual mucosa was significantly lower in the dry mouth group 27.2 ± 4.9 thanthat in the healthy group 29.5 ± 3.1, AUC = 0.653. When a lingual mucosa moisturedegree of 31.0 or higher was defined as normal, less than 27.0 as dry mouth, and27.0 to less than 31.0 as borderline zone of dry mouth, both the sensitivity andthe specificity for the diagnosis of dry mouth were close to 80%. Conclusion: Theseresults suggest that the oral moisture-checking device is a usable screening devicefor dry mouth.


Dry Mouth; Oral Moisture-Checking Device; ROC Analysis

Cite this paper

Fukushima, Y. , Yoda, T. , Kokabu, S. , Araki, R. , Murata, T. , Kitagawa, Y. , Omura, K. , Toya, S. , Ito, K. , Funayama, S. , Iwabuchi, H. , Asano, K. , Imai, Y. , Negishi, A. , Yokoo, S. , Matsumoto, G. , Kubota, E. , Watanabe, H. , Kusama, M. , Onizawa, K. , Goto, T. , Nakamura, S. , Nakazawa, R. , Harada, K. and Fujibayashi, T. 2013 Evaluation of an oral moisture-checking device for screening dry mouth. Open Journal of Stomatology, 3, 440-446. doi: 10.4236-ojst.2013.38073.

Autor: Yosuke Fukushima, Tetsuya Yoda, Shoichiro Kokabu, Ryuichiro Araki, Tsubasa Murata, Yoshimasa Kitagawa, Ken Omura, Shuji Toya, Kay

Fuente: http://www.scirp.org/


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