Impact of Postoperative Radiotherapy and Chemotherapy on Survival for Patients with Node Positive Oral CancerReportar como inadecuado




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Purpose: The aim of the present study isto compare between the use of post-operative concurrent chemotherapy andradiotherapy alone on survival for patients with high risk oral cavity tumorsat the National cancer Institute of Egypt, undergoing surgery and receivingadjuvant treatment. Patients and Methods: This is a retrospective study, which was carried out at the National CancerInstitute Cairo University on patients with node positive oral cavity cancerdiagnosed between the year 2000 and 2008. The study included 60 patients 45males and 15 females with median age 57 years old. The patients underwentsurgery, followed by postoperative radiotherapy 60 Gy-6 weeks versuspostoperative radiotherapy 60 Gy-6 weeks with concurrent cisplatin 100 mg-m2 at day 1, day 22 and day 43. Results: Regarding use of concurrent chemotherapy, there was a significant difference inoverall survival rate and locoregional control favoring patients who receivedconcurrent chemotherapy and radiotherapy, 3 years and 5 years overall survivalrates respectively were 53.8% and 40.4% compared to 37.5% and 26.3% forpatients who didn’t receive any chemotherapy with p 57 years with p



Autor: Mohamed Mahmoud, Tarek Shouman, Hesham Elhosseny, Mona Aboelenin, Mohamed Amin

Fuente: http://www.scirp.org/



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