A Serological Survey of Antibodies to H5, H7 and H9 Avian Influenza Viruses amongst the Duck-Related Workers in Beijing, ChinaReportar como inadecuado




A Serological Survey of Antibodies to H5, H7 and H9 Avian Influenza Viruses amongst the Duck-Related Workers in Beijing, China - Descarga este documento en PDF. Documentación en PDF para descargar gratis. Disponible también para leer online.

The continued spread of highly pathogenic avian influenza HPAI viruses of H5 and H7 subtypes and low pathogenic avian influenza LPAI viruses of H5, H7 and H9 subtypes in birds and the subsequent infections in humans pose an ongoing pandemic threat. It has been proposed that poultry workers are at higher risk of exposure to HPAI or LPAI viruses and subsequently infection due to their repeated exposure to chickens or domestic waterfowl. The aim of this study was to examine the seroprevalence of antibodies against H5, H7 and H9 viruses amongst duck-related workers in Beijing, China and the risk factors associated with seropositivity. In March, 2011, 1741 participants were recruited from 1 commercial duck-breeding farms; 2 private duck-breeding farms; and 3 duck-slaughtering farms. Local villagers who bred ducks in their backyards were also recruited. A survey was administered by face-to-face interview, and blood samples were collected from subjects for antibody testing against H5, H7 and H9 viruses. We found that none of the subjects were seropositive for either H5 or H7 viruses, and only 0.7% 12-1741 had antibody against H9. A statistically significant difference in H9 antibody seroprevalence existed between the various categories of workers P = 0.005, with the highest figures recorded amongst the villagers 1.7%. Independent risk factors associated with seropositivity toinfection with H9 virus included less frequent disinfection of worksite OR, 5.13 95% CI, 1.07–24.58; P = 0.041; ≤ twice monthly versus>twice monthly and handling ducks with wounds on hands OR, 4.13 95% CI, 1.26–13.57; P = 0.019. Whilst the risk of infection with H5, H7 and H9 viruses appears to be low among duck-related workers in Beijing, China, ongoing monitoring of infection with the H9 virus is still warranted, especially amongst villagers who breed backyard ducks to monitor for any changes.



Autor: Peng Yang, Chunna Ma, Weixian Shi, Shujuan Cui, Guilan Lu, Xiaomin Peng, Daitao Zhang, Yimeng Liu, Huijie Liang, Yi Zhang, Li Zha

Fuente: http://plos.srce.hr/



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