Prevalence of microalbuminuria in type 2 diabetes patients in Tirana, a preliminary multicenter studyReportar como inadecuado




Prevalence of microalbuminuria in type 2 diabetes patients in Tirana, a preliminary multicenter study - Descarga este documento en PDF. Documentación en PDF para descargar gratis. Disponible también para leer online.

Background:Microalbuminuria is often the first sign of renal involvement predicting overtnephropathy. For this reason, monitoring microalbuminuria and other riskfactors associated with this condition is important to take measures to preventor postpone overt nephropathy. This study aimed to investigate the prevalenceof microalbuminuria in type 2 diabetes patients attending three diabetescenters in Tirana city. Patients and Methods: Two hundred and twenty patientswith type 2 diabetes attending diabetes centers in Tirana were recruited inthis crosssectional study. Medical records were used to collect data onduration of diabetes, waist circumference,history of hypertension, smoking. Blood samples were drawn after 12 hovernight fasting to measure glycosylated hemoglobin HbA1c, serum cholesterol, triglyceride andcreatinine. Microalbuminuria was assessed using dipstick kits in earlymorning urine samples. Results: The prevalence of normoalbuminuria was 58.3%,microalbuminuria 38.6% and macroalbuminuria 3.1%. Systolic and diastolicblood pressure p < 0.01, HbA1cp <0.01 and fasting plasma glucose p < 0.001 were significantly higher in microalbuminuric than in normoalbuminuricsubjects. Multiple logistic regression analysis using microalbuminuria as thedependent variable in males shows that independent risk factors for diabetespatients with microalbuminuria were duration of diabetes, systolic bloodpressure and waist circumference. We found that the OR for microalbuminuria became statistically significantly increased only at 16 years after the diagnosisof type 2 diabetes. At this time, 43.7% of patients had microalbuminuria. Conclusions: Wefound a high proportion of type 2 diabetes patients with microalbuminuriawhich raises implications for health policy inAlbania. This calls for early detectionand good control of diabetes to reduce the burden of diabetic kidney diseasein the future. Screening programs and optimized control of modifiable riskfactors are needed to reduce the risk of diabetic nephropathy.

KEYWORDS

Microalbuminuria; Type 2 Diabetes; Epidemiology; Albania

Cite this paper

Pasko, N. , Toti, F. , Zekollari, E. , Strakosha, A. , Kacori, V. and Thereska, N. 2013 Prevalence of microalbuminuria in type 2 diabetes patients in Tirana, a preliminary multicenter study. Journal of Diabetes Mellitus, 3, 145-149. doi: 10.4236-jdm.2013.33022.





Autor: Nevi Pasko, Florian Toti, Ervin Zekollari, Arjana Strakosha, Viola Kacori, Nestor Thereska

Fuente: http://www.scirp.org/



DESCARGAR PDF




Documentos relacionados