Cytokines, estradiol and progesterone in the plasma of women of reproductive age with pelvic inflammatory disease in remissionReportar como inadecuado




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In the course of the study there were examined cytokinelevels of pro-inflammatory and anti-inflammatory activity IL-1b, IL-4,IL-6, IL-8, IL-10, IFN-g, G-GSF,and also the levels of progesterone and estradiol in the blood serum with a viewto study the pathogenic characteristics of a chronic inflammatory process ofthe pelvic organs in remission. It was shown that the remission of the diseaseis characterized by the significant increase in the concentrations ofpro-inflammatory cytokines IL-6, IL-8, and also increase of inducers activationof the immune response of the immune response IL-4 and IFN-g, accompaniedby a decrease in the concentration of sex hormones. In women with chronicinflammatory diseases of urogenital sphere in remission tested active immunologicalprocess and violation of the synthesis of sex hormones. Revealed changespredispose to the emergence disorders of reproductive health.

KEYWORDS

Immune Response; Sex Hormones; Chronic Inflammation; Remission; Cytokines

Cite this paper

Trunov, A. , Obukhova, O. , Gorbenko, O. , Shvayk, A. and Trunova, L. 2013 Cytokines, estradiol and progesterone in the plasma of women of reproductive age with pelvic inflammatory disease in remission. Advances in Bioscience and Biotechnology, 4, 727-730. doi: 10.4236-abb.2013.46096.





Autor: Aleksandr Trunov, Olga Obukhova, Olga Gorbenko, Alya Shvayk, Liliya Trunova

Fuente: http://www.scirp.org/



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