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Objective: Studies available on cognitive function amongschool-aged HIV-infected African and in particular Nigerian children are few. The purpose of the study was toassess the neurocognitive function of a group of HIV-infected schoolaged 6 - 15 years children using the Raven’sStandard Progressive Matrices RPM. Method: Cognitive assessments of 69 HIVpositive children and 69 age- and sex-matched apparently healthy HIV negativecontrol children were performed usingthe Raven’s Standard Progressive Matrices RPM. The children were subdividedPiaget’s developmental staging into two sub-groups: the concrete operationstage 6 - 11 years and the formal operation stage 12 - 15 years for analysis. Result: The mean RPM score for the HIV positive childrenwas 18.2 8.0 - 47.0, SD 9.8 which was significantly lower than the score of 27.2 8.0 - 52.0, SD 13.8 for the HIV negativechildren p < 0.001. On the RPM grading and using the HIV negative childrenas the standard, 56.5% of the HIV positive children had cognitive performance at below average tointellectually defective range. Conclusion: School-aged HIV positive children had significantly lower cognitive scorescompared with age and gender-matched HIV negative children. Routine neuropsychological evaluation of allschool-aged HIV-infected children is recommended. Early detection of cognitiveimpairment will help inplanning appropriate interventions.


Pediatric HIV; Cognitive Assessment; School-Age Children; Ravens Progressive Matrices; Nigeria

Cite this paper

G. Boyede, F. Lesi, C. Ezeaka and C. Umeh -The Neurocognitive Assessment of HIV-Infected School-Aged Nigerian Children,- World Journal of AIDS, Vol. 3 No. 2, 2013, pp. 124-130. doi: 10.4236-wja.2013.32017.

Autor: Gbemisola O. Boyede, Foluso E. A. Lesi, Chinyere V. Ezeaka, Charles S. Umeh



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