HCV and HIV Infection among Heroin Addicts in Methadone Maintenance Treatment MMT and Not in MMT in Changsha and Wuhan, ChinaReportar como inadecuado




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Objective

To compare HCV and HIV infection among heroin addicts in MMT and not in MMT in two large cities in central China.

Methods

A total of 541 heroin addicts were recruited from MMT clinics and voluntary detoxification centers in Changsha and Wuhan, China. Structured questionnaires collected data on their socio-demographics, clinical status, risk behaviors, and their knowledge of HIV. Their HIV serostatus and Hepatitis C virus HCV serostatus were determined by testing antibodies in blood serum.

Results

We observed a higher prevalence of HCV infection among MMT heroin addicts 82.3% than that in the non-MMT group 50.6%. However, our findings indicated that the heroin addicts in MMT had less drug or sexual HIV-HCV risk behaviors and more knowledge about HIV than non-MMT addicts. The heroin addicts in MMT had a significantly higher percentage of individuals who always used condoms 44.9% compared with patients in the non-MMT group 14.6%, p = 0.039, and they had more knowledge about HIV than non-MMT individuals p<.001. The percentage of HIV-positive addicts in the MMT group 0.7% and non-MMT group 0.8% were almost same.

Conclusion

Our study indicated that the rate of HCV infection among heroin addicts among MMT or non-MMT settings in central China is very high. The non-MMT heroin addicts have higher risk of becoming infected with HCV in the future, while at present they have lower rates of HCV infection than MMT heroin addicts. Although rates of HIV infection among MMT and non-MMT heroin addicts are low now, they are all at great risk of becoming infected with HIV in the future, especially for non-MMT heroin addicts. We should use the MMT sites as a platform to improve the control of HCV and HIV infection in heroin addicts.



Autor: Xuyi Wang, Linxiang Tan, Yi Li, Yao Zhang, Dongyi Zhou, Tieqiao Liu, Wei Hao

Fuente: http://plos.srce.hr/



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