Ezetimibe Completely Replaced LDL-Apheresis for the Treatment of Familial Hypercholesterolemia and Coronary Artery Disease after CABG—A Case ReportReportar como inadecuado




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Intensive treatment ofhyperlipidemia is an important factor in the prevention of cardiovasculardisease. Among several therapies, statins are well recognized as playing a central role, although low densitylipoprotein bound cholesterol-apheresis can be used to treat very severe casesof familial hypercholesterolemia. However, statins are not always effective ontheir own and, recently, ezetimibe has emerged as a unique anti- hypercholesterolemicdrug that acts as a cholesterol transporter inhibitor; its role is onlypartially understood. I experienced rare case that appeared to benefit fromezetimibe therapy, and report them as they help increase our knowledgeof this novel drug.

KEYWORDS

Ezetimibe; Familial Hypercholesterolemia; Statins; LDL-Apheresis; Coronary Artery Disease

Cite this paper

Yokoyama, I. 2013 Ezetimibe Completely Replaced LDL-Apheresis for the Treatment of Familial Hypercholesterolemia and Coronary Artery Disease after CABG—A Case Report. Journal of Biomedical Science and Engineering, 6, 232-235. doi: 10.4236-jbise.2013.62A028.





Autor: Ikuo Yokoyama

Fuente: http://www.scirp.org/



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