Validation of a Risk-Based Biomarker-Enhanced Scoring System for Lower Respiratory Tract Infections OPTIMA I Basel—An Observational SurveyReportar como inadecuado




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Background: Despiteits recommendation in management guide lines for community acquired pneumonia CAP, the CURB65 score is frequently not followed for disposition decisions inclinical routine. We therefore proposed an improvedCURB65 A score, supplemented by proadre nome dull in ProADMlevels for patients with CAP and other lower respiratory tract infectionsLRTIs. In this study, we vali dated this risk based biomarker enhanced disposition in patients with LRTIspresenting to the emergency department of the University Hospitalof Basel. Methods: In this prospective observational cohort studyof 85 patients presenting with LRTIs, site of care was decided by thephysicians in charge according to their judgement. Retro spectively the CURB65 A score wascalculated and a virtual disposition assigned. This was compared with theexisting disposition in order to identify efficacy of the novel risk basedbiomarker enhanced disposition. Results: The novel disposition criteria considered 14patients suitable for outpatient treatment compared to 11 in the current disposition p = 0.5. It detected 7 patients to bebest treated outside the hospital for nursing reasons, while the currentdisposition detected only 1 patient requiring geriatric care p = 0.09. Further, it decreased regularhospitalizations considerably 32 vs. 64, p



Autor: Richard X. Sousa Da Silva, Frank Dusemund, Christian Nickel, Roland Bingisser, Andreas Huber, Beat Müller, Werner C. Albrich

Fuente: http://www.scirp.org/



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