History of Vitamin A Supplementation Reduces Severity of Diarrhea in Young Children Admitted to Hospital with Diarrhea and PneumoniaReportar como inadecuado




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Background: Although the role of vitamin A in childhood pneumonia in association with diarrhea is not fully proven, we did not find any published data demonstrating the impact of lack of vitamin A supplementation in under-five children who present with the co-morbidities of pneumonia and diarrhea. This study examined whether previous vitamin A supplementation was associated with reduced severity and duration of diarrhea and pneumonia for children presenting with both illnesses. Methods: All admitted children n = 189 aged 0 - 59 months to the Special Care Ward of the Dhaka Hospital of icddr,b with diarrhea and radiological pneumonia from September-December 2007 were enrolled. We compared clinical features of the children who received n = 96 and did not receive n = 93 high potency capsule vitamin A supplementation during previous immunization according to EPI schedule. Results: In logistic regression analysis, after adjusting for potential confounders such as respiratory rate, lower chest wall in-drawing, severe wasting and systolic blood pressure, vitamin A non-supplemented children with pneumonia and diarrhea more often presented in their early infancy 95% CI 1.01 - 1.09, had duration of diarrhea for >4 days 95% CI 1.79 - 11.88, had clinical dehydration 95% CI 1.2 - 5.63, and more often required hospitalization for >7 days 95% CI 1.03 - 8.87. But, there was no significant difference in the clinical features of pneumonia, such as history of cough, respiratory rate, lower chest wall in-drawing, nasal flaring, head nodding, grunting respiration, cyanosis, and inability to drink between the groups. Conclusion: Lack of vitamin A supplementation in under-five children with radiological pneumonia and diarrhea is independently associated with young infancy, duration of diarrhea for >4 days, dehydration and hospitalization for >7 days which underscores the importance of routine supplementation of vitamin A in young infancy. However, lack of vitamin A supplementation did not influence any clinical signs of pneumonia.

KEYWORDS

Bangladesh; Diarrhea; Children; Lower Chest Wall In-Drawing; Pneumonia; Vitamin A Supplementation

Cite this paper

M. Chisti, M. Salam, A. Faruque, H. Ashraf, P. Bardhan, S. Das, S. Huq, F. Chowdhury, S. Islam and T. Ahmed -History of Vitamin A Supplementation Reduces Severity of Diarrhea in Young Children Admitted to Hospital with Diarrhea and Pneumonia,- Food and Nutrition Sciences, Vol. 4 No. 2, 2013, pp. 150-155. doi: 10.4236-fns.2013.42021.





Autor: Mohammod J. Chisti, Mohammed A. Salam, Abu S. G. Faruque, Hasan Ashraf, Pradip K. Bardhan, Sumon K. Das, Sayeeda Huq, Fahmida Cho

Fuente: http://www.scirp.org/



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