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Collegium antropologicum, Vol.34 No.4 December 2010. -

The aim of study was to compare the impact of coronary risk factors on the incidence of acute myocardial infarction MI between Croatia, Central and Eastern Europe, and the rest of the world. As a part of the large international INTERHEART case-control study of acute MI in 52 countries 15,152 cases and 14,820 controls we have investigated the relationship between several known risk factors smoking, history of hypertension or diabetes, waist-hip ratio, dietary patterns, physical activity, consumption of alcohol, blood apolipoproteins, and psychosocial factors and MI among patients without previously known coronary heart disease in Southern Croatia. The main identified MI risk factors in Southern Croatia were heavy smoking >20 cig-day; OR 3.86; 95% CI 2.31–6.46, diabetes mellitus OR 2.83; 95% CI 1.58–5.23, abnormal ratio of B-100 and A-1 apolipoproteins OR 2.23; 95% CI 1.28–3.89, elevated waist to hip ratio OR 1.96; 95% CI 1.21–3.18, and arterial hypertension OR 1.68; 95% CI 1.15–2.45. Protective was moderate alcohol consumption OR 0.63; 95% CI 0.40–0.99. The prevalence of major MI risk factors in Croatia is similar to that in the surrounding countries and in the world, accounting for over 90% of the population attributable risk. However, physical activity, dietary and psychosocial factors are seemingly less important in this country, while moderate alcohol consumption is more protective than regionally or globally.

risk factors; myocardial infarction; Croatia; INTERHEART; family medicine

Autor: Vedran Carević - Marion Kuzmanić - Mirjana Rumboldt - Zvonko Rumboldt -



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