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Atrial fibrillation andheart failure often coexist in patients with advanced heart failure symptoms. The result, in addition toa significant impact on quality of life, is an increase in the risk of aadverse clinical outcomes including stroke, hospitalization and overallmortality. Pharmacological therapy for atrial fibrillation in the heartfailure population remains limited due to sub-optimal drug efficacy and alikely increased mortality due to pro-arrhythmia. Atrial fibrillation ablation,since it allows for therapy without the need for toxic medication, has thepotential to become mainstream treatment inpatients with drug refractory, symptomatic atrial fibrillation and heartfailure. Randomized studies and observational data suggest that atrialfibrillation ablation provides superior rhythm control to anti-arrhythmicdrugs. Atrial fibrilla- tion ablation is relatively safe and may result in improvement of left ventricularfunction and quality of life. Ongoingstudies are attempting to assess a number of outcome measures to help defineits role in the heart failure patient population. This review focuses on atrialfibrillation ablation in patients with congestive heart failure, and summarizesthe results of available literature.

KEYWORDS

Atrial Fibrillation; Ablation; Heart Failure

Cite this paper

Amin, M. , Sterns, L. , Leather, R. and Tang, A. 2013 Atrial fibrillation ablation in patients with heart failure review. World Journal of Cardiovascular Diseases, 3, 49-57. doi: 10.4236-wjcd.2013.31011.





Autor: Mohammad I. Amin, Laurence D. Sterns, Richard A. Leather, Anthony S. Tang

Fuente: http://www.scirp.org/



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