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The Association Between Hip Fracture and Hip Osteoarthritis: A Case-Control Study


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Citation

Franklin, Jonas, Martin Englund, Torvaldur Ingvarsson, Stefan Lohmander. -The Association Between Hip Fracture and Hip Osteoarthritis: A Case-Control Study.- BMC Musculoskeletal Disorders 11:274. 2010

Abstract

BACKGROUND: There have been reports both supporting and refuting an inverse relationship between hip fracture and hip osteoarthritis OA. We explore this relationship using a case-control study design. METHODS: Exclusion criteria were previous hip fracture same side or contralateral side, age younger than 60 years, foreign nationality, pathological fracture, rheumatoid arthritis and cases were radiographic examinations were not found in the archives. We studied all subjects with hip fracture that remained after the exclusion process that were treated at Akureyri University Hospital, Iceland 1990-2008, n = 562 74% women. Hip fracture cases were compared with a cohort of subjects with colon radiographs, n = 803 54% women to determine expected population prevalence of hip OA. Presence of radiographic hip OA was defined as a minimum joint space of 2.5 mm or less on an anteroposterior radiograph, or Kellgren and Lawrence grade 2 or higher. Possible causes of secondary osteoporosis were identified by review of medical records. RESULTS: The age-adjusted odds ratio OR for subjects with hip fracture having radiographic hip OA was 0.30 95% confidence interval 95% CI 0.12-0.74 for men and 0.33 95% CI 0.19-0.58 for women, compared to controls. The probability for subjects with hip fracture and hip OA having a secondary cause of osteoporosis was three times higher than for subjects with hip fracture without hip OA. CONCLUSION: The results of our study support an inverse relationship between hip fractures and hip OA.Rights

Copyright 2010 Franklin et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http:-creativecommons.org-licenses-by-2.0, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

MED: Medicine Papers -



Autor: Franklin, Jonas - Englund, Martin - Ingvarsson, Torvaldur - Lohmander, Stefan - -

Fuente: https://open.bu.edu/







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